|
KMID : 0383820120730060320
|
|
Tuberculosis and Respiratory Diseases
2012 Volume.73 No. 6 p.320 ~ p.324
|
|
|
Sarcoidosis Presenting with Massive Pleural Effusion and Elevated Serum and Pleural Fluid Carbohydrate Antigen-125 Levels
|
|
Lee In-Seon
Kim Sae-Byul
Moon Chan-Soo
Jung Sung-Mo
Kim Song-Yee
Kim Eun-Young
Jung Ji-Ye
Kang Young-Ae
Kim Young-Sam
Kim Se-Kyu
Chang Joon
Park Moo-Suk
|
|
|
Abstract
|
|
|
|
A 55-year-old woman was admitted for an elevated serum carbohydrate antigen-125 (CA-125) level, and a left pleural effusion, which were detected at a routine health examination. Computed tomography of the chest was performed upon admission, revealing extensive bilateral paratracheal and mediastinal lymph node enlargement with a massive left-sided pleural effusion. Subsequent analysis of the pleural fluid demonstrated consistency with an exudate, no evidence of malignant cells, and a normal adenosine deaminase. However, the pleural fluid and serum CA-125 levels were 2,846.8 U/mL and 229.5 U/mL, respectively. A positron emission tomography did not reveal any primary focus of malignancy. Finally, a surgical mediastinoscopic biopsy of several mediastinal lymph nodes was performed, revealing non-necrotizing granulomas, consistent with sarcoidosis. After a month of treatment of prednisolone, the left pleural effusion had resolved, and after 2 months the serum CA-125 level was normalized.
|
|
|
KEYWORD
|
|
|
Sarcoidosis, Pleural Effusion, CA-125 Antigen
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
  
|
|